Ontology highlight
ABSTRACT:
SUBMITTER: van Twillert I
PROVIDER: S-EPMC5238437 | biostudies-other | 2017 Jan
REPOSITORIES: biostudies-other
van Twillert Inonge I Bonačić Marinović Axel A AA Kuipers Betsy B van Gaans-van den Brink Jacqueline A M JA Sanders Elisabeth A M EA van Els Cécile A C M CA
Scientific reports 20170116
Capturing the complexity and waning patterns of co-occurring immunoglobulin (Ig) responses after clinical B. pertussis infection may help understand how the human host gradually loses protection against whooping cough. We applied bi-exponential modelling to characterise and compare B. pertussis specific serological dynamics in a comprehensive database of IgG, IgG subclass and IgA responses to Ptx, FHA, Prn, Fim2/3 and OMV antigens of (ex-) symptomatic pertussis cases across all age groups. The d ...[more]