Ontology highlight
ABSTRACT:
SUBMITTER: Champelovier D
PROVIDER: S-EPMC5318884 | biostudies-other | 2017 Feb
REPOSITORIES: biostudies-other
Scientific reports 20170221
Adaptive optics is a promising technique for the improvement of microscopy in tissues. A large palette of indirect and direct wavefront sensing methods has been proposed for in vivo imaging in experimental animal models. Application of most of these methods to complex samples suffers from either intrinsic and/or practical difficulties. Here we show a theoretically optimized wavefront correction method for inhomogeneously labeled biological samples. We demonstrate its performance at a depth of 20 ...[more]