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Cell adhesion: a FERM grasp of the tail sorts out integrins.


ABSTRACT: As well as modulating integrin activation, a conserved NPxY motif in integrin cytoplasmic tails that binds the FERM-domain-containing proteins kindlin and sorting nexin 17 plays pivotal roles in integrin recycling and degradation.

SUBMITTER: Brahme NN 

PROVIDER: S-EPMC5507346 | biostudies-other | 2012 Sep

REPOSITORIES: biostudies-other

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