Cell adhesion: a FERM grasp of the tail sorts out integrins.
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ABSTRACT: As well as modulating integrin activation, a conserved NPxY motif in integrin cytoplasmic tails that binds the FERM-domain-containing proteins kindlin and sorting nexin 17 plays pivotal roles in integrin recycling and degradation.
SUBMITTER: Brahme NN
PROVIDER: S-EPMC5507346 | biostudies-other | 2012 Sep
REPOSITORIES: biostudies-other
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