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Enantiomerically enriched tris(boronates): readily accessible conjunctive reagents for asymmetric synthesis.

ABSTRACT: The catalytic enantioselective diboration of vinyl boronate esters furnishes chiral tris(boronates) in a selective fashion. Subsequent deborylative alkylation occurs in a diastereoselective fashion, both for intermolecular and intramolecular processes.

SUBMITTER: Coombs JR

PROVIDER: S-EPMC5539535 | biostudies-other | 2014 Nov

REPOSITORIES: biostudies-other

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Enantiomerically enriched tris(boronates): readily accessible conjunctive reagents for asymmetric synthesis.

Coombs John R JR Zhang Liang L Morken James P JP

Journal of the American Chemical Society 20141111 46

The catalytic enantioselective diboration of vinyl boronate esters furnishes chiral tris(boronates) in a selective fashion. Subsequent deborylative alkylation occurs in a diastereoselective fashion, both for intermolecular and intramolecular processes. ...[more]

PMID: 25387002

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