Ontology highlight
ABSTRACT:
SUBMITTER: Zhang JJ
PROVIDER: S-EPMC5580898 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Zhang Jing-Jing JJ Hao Jun-Jun JJ Zhang Yu-Ru YR Wang Yan-Li YL Li Ming-Yi MY Miao Hui-Lai HL Zou Xiao-Ju XJ Liang Bin B
Journal of lipid research 20170714 9
Maintenance of lipid homeostasis is crucial for cells in response to lipid requirements or surplus. The SREBP transcription factors play essential roles in regulating lipid metabolism and are associated with many metabolic diseases. However, SREBP regulation of lipid metabolism is still not completely understood. Here, we showed that reduction of SBP-1, the only homolog of SREBPs in <i>Caenorhabditis elegans</i>, surprisingly led to a high level of zinc. On the contrary, zinc reduction by mutati ...[more]