Ontology highlight
ABSTRACT:
SUBMITTER: Tolstykh GP
PROVIDER: S-EPMC5614542 | biostudies-other | 2017 Mar
REPOSITORIES: biostudies-other
Tolstykh Gleb P GP Thompson Gary L GL Beier Hope T HT Steelman Zachary A ZA Ibey Bennett L BL
Biochemistry and biophysics reports 20161111
Cell swelling and blebbing has been commonly observed following nanosecond pulsed electric field (nsPEF) exposure. The hypothesized origin of these effects is nanoporation of the plasma membrane (PM) followed by transmembrane diffusion of extracellular fluid and disassembly of cortical actin structures. This investigation will provide evidence that shows passive movement of fluid into the cell through nanopores and increase of intracellular osmotic pressure are not solely responsible for this ob ...[more]