Ontology highlight
ABSTRACT:
SUBMITTER: Golato T
PROVIDER: S-EPMC5636817 | biostudies-other | 2017 Oct
REPOSITORIES: biostudies-other
Golato Tyler T Brenerman Boris B McNeill Daniel R DR Li Jianfeng J Sobol Robert W RW Wilson David M DM
Scientific reports 20171011 1
Base excision repair (BER) is the predominant pathway for coping with most forms of hydrolytic, oxidative or alkylative DNA damage. Measuring BER capacity in living cells is valuable for both basic science applications and epidemiological studies, since deficiencies in this pathway have been associated with cancer susceptibility and other adverse health outcomes. At present, there is an ongoing effort to develop methods to effectively quantify the rate of BER as a whole. We present a variation o ...[more]