Ontology highlight
ABSTRACT:
SUBMITTER: Han Y
PROVIDER: S-EPMC5670236 | biostudies-other | 2017 Nov
REPOSITORIES: biostudies-other
Nature communications 20171103 1
Characterizing the long-term nanometer-scale interactions between lysosomes and mitochondria in live cells is essential for understanding their functions but remains challenging due to limitations of the existing fluorescent probes. Here, we develop cell-permeable organic fluorescent probes for lysosomes with excellent specificity and high photostability. We also use an existing Atto 647N dye with high brightness and excellent photostability to achieve specific labeling of mitochondria in live c ...[more]