Ontology highlight
ABSTRACT:
SUBMITTER: Iraola G
PROVIDER: S-EPMC5678084 | biostudies-other | 2017 Nov
REPOSITORIES: biostudies-other
Iraola Gregorio G Forster Samuel C SC Kumar Nitin N Lehours Philippe P Bekal Sadjia S García-Peña Francisco J FJ Paolicchi Fernando F Morsella Claudia C Hotzel Helmut H Hsueh Po-Ren PR Vidal Ana A Lévesque Simon S Yamazaki Wataru W Balzan Claudia C Vargas Agueda A Piccirillo Alessandra A Chaban Bonnie B Hill Janet E JE Betancor Laura L Collado Luis L Truyers Isabelle I Midwinter Anne C AC Dagi Hatice T HT Mégraud Francis F Calleros Lucía L Pérez Ruben R Naya Hugo H Lawley Trevor D TD
Nature communications 20171108 1
Campylobacter fetus is a venereal pathogen of cattle and sheep, and an opportunistic human pathogen. It is often assumed that C. fetus infection occurs in humans as a zoonosis through food chain transmission. Here we show that mammalian C. fetus consists of distinct evolutionary lineages, primarily associated with either human or bovine hosts. We use whole-genome phylogenetics on 182 strains from 17 countries to provide evidence that C. fetus may have originated in humans around 10,500 years ago ...[more]