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Anti-HIV Passive Immunization: New Weapons in the Arsenal.


ABSTRACT: Anti-HIV passive immunization with human neutralizing monoclonal antibodies (nmAbs) has made exciting gains: (i) identification of the HIV envelope V2 apex as a new in vivo protective epitope, (ii) a novel clade C SHIV for challenge studies, and (iii) a highly protective, trispecific nmAb. Potent, broad-spectrum protection by nmAbs holds promise.

SUBMITTER: Ruprecht RM 

PROVIDER: S-EPMC5701852 | biostudies-other | 2017 Dec

REPOSITORIES: biostudies-other

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Anti-HIV Passive Immunization: New Weapons in the Arsenal.

Ruprecht Ruth M RM  

Trends in microbiology 20171030 12


Anti-HIV passive immunization with human neutralizing monoclonal antibodies (nmAbs) has made exciting gains: (i) identification of the HIV envelope V2 apex as a new in vivo protective epitope, (ii) a novel clade C SHIV for challenge studies, and (iii) a highly protective, trispecific nmAb. Potent, broad-spectrum protection by nmAbs holds promise. ...[more]

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