Ontology highlight
ABSTRACT:
SUBMITTER: Franquelim HG
PROVIDER: S-EPMC5824810 | biostudies-other | 2018 Feb
REPOSITORIES: biostudies-other
Nature communications 20180223 1
Membrane sculpting and transformation is essential for many cellular functions, thus being largely regulated by self-assembling and self-organizing protein coats. Their functionality is often encoded by particular spatial structures. Prominent examples are BAR domain proteins, the 'banana-like' shapes of which are thought to aid scaffolding and membrane tubulation. To elucidate whether 3D structure can be uncoupled from other functional features of complex scaffolding proteins, we hereby develop ...[more]