Ontology highlight
ABSTRACT:
SUBMITTER: Fuster JJ
PROVIDER: S-EPMC5826570 | biostudies-other | 2018 Feb
REPOSITORIES: biostudies-other
Fuster José J JJ Walsh Kenneth K
Circulation research 20180201 3
Increasing evidence shows that conventional cardiovascular risk factors are incompletely predictive of cardiovascular disease, particularly in elderly individuals, suggesting that there may still be unidentified causal risk factors. Although the accumulation of somatic DNA mutations is a hallmark of aging, its relevance in cardiovascular disease or other age-related conditions has been, with the exception of cancer, largely unexplored. Here, we review recent clinical and preclinical studies that ...[more]