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High Sensitivity of T-Ray for Thrombus Sensing.

ABSTRACT: Atherosclerotic plaque rupture or erosion and subsequent development of platelet-containing thrombus formation is the fundamental cause of cardiovascular disease, which is the most common cause of death and disability worldwide. Here we show the high sensitivity of 200-270?GHz T-ray to distinguish thrombus formation at its early stage from uncoagulated blood. A clinical observational study was conducted to longitudinally monitor the T-ray absorption constant of ex-vivo human blood during the thrombus formation from 29 subjects. Compared with the control group (28 subjects) with uncoagulated blood samples, our analysis indicates the high sensitivity of 200-270?GHz T-Ray to detect thrombus with a low p-value?

SUBMITTER: Sun CK

PROVIDER: S-EPMC5834502 | biostudies-other | 2018 Mar

REPOSITORIES: biostudies-other

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High Sensitivity of T-Ray for Thrombus Sensing.

Sun Chi-Kuang CK Chen Hui-Yuan HY Tseng Tzu-Fang TF You Borwen B Wei Ming-Liang ML Lu Ja-Yu JY Chang Ya-Lei YL Tseng Wan-Ling WL Wang Tzung-Dau TD

Scientific reports 20180302 1

Atherosclerotic plaque rupture or erosion and subsequent development of platelet-containing thrombus formation is the fundamental cause of cardiovascular disease, which is the most common cause of death and disability worldwide. Here we show the high sensitivity of 200-270 GHz T-ray to distinguish thrombus formation at its early stage from uncoagulated blood. A clinical observational study was conducted to longitudinally monitor the T-ray absorption constant of ex-vivo human blood during the thr ...[more]

PMID: 29500384

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