Ontology highlight
ABSTRACT:
SUBMITTER: Liao G
PROVIDER: S-EPMC5860976 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Liao Guojian G Wang Yina Y Liu Tong-Bao TB Kohli Gurkirat G Qian Weidong W Shor Erika E Subbian Selvakumar S Xue Chaoyang C
Fungal genetics and biology : FG & B 20180203
Cryptococcus neoformans is the most common cause of deadly fungal meningitis. This fungus has a complex inositol acquisition and utilization system, and our previous studies have shown the importance of inositol utilization in cryptococcal development and virulence. However, how inositol utilization is regulated in this fungus remains unknown. In this study, we found that inositol, irrespective of the presence of glucose in the media, represses the expression of C. neoformans genes involved in i ...[more]