Ontology highlight
ABSTRACT:
SUBMITTER: Manda B
PROVIDER: S-EPMC5963837 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Manda Bhargavi B Mir Hina H Gangwar Ruchika R Meena Avtar S AS Amin Shrunali S Shukla Pradeep K PK Dalal Kesha K Suzuki Takuya T Suzuki Takuya T Rao RadhaKrishna R
Journal of cell science 20180406 7
The apical junctional complex (AJC), which includes tight junctions (TJs) and adherens junctions (AJs), determines the epithelial polarity, cell-cell adhesion and permeability barrier. An intriguing characteristic of a TJ is the dynamic nature of its multiprotein complex. Occludin is the most mobile TJ protein, but its significance in TJ dynamics is poorly understood. On the basis of phosphorylation sites, we distinguished a sequence in the C-terminal domain of occludin as a regulatory motif (OR ...[more]