Ontology highlight
ABSTRACT:
SUBMITTER: Liu CH
PROVIDER: S-EPMC5963847 | biostudies-other | 2018 Apr
REPOSITORIES: biostudies-other
Liu Che-Hsiung CH Bollepalli Murali K MK Long Samuel V SV Asteriti Sabrina S Tan Julie J Brill Julie A JA Hardie Roger C RC
Journal of cell science 20180419 8
Phototransduction in <i>Drosophila</i> is mediated by phospholipase C-dependent hydrolysis of PIP<sub>2-</sub>, and is an important model for phosphoinositide signalling. Although generally assumed to operate by generic machinery conserved from yeast to mammals, some key elements of the phosphoinositide cycle have yet to be identified in <i>Drosophila</i> photoreceptors. Here, we used transgenic flies expressing fluorescently tagged probes (P4M and Tb<sup>R332H</sup>), which allow <i>in vivo</i> ...[more]