Ontology highlight
ABSTRACT:
SUBMITTER: Rotskoff GM
PROVIDER: S-EPMC6016822 | biostudies-other | 2018 Jun
REPOSITORIES: biostudies-other
Rotskoff Grant M GM Geissler Phillip L PL
Proceedings of the National Academy of Sciences of the United States of America 20180604 25
Cyanobacteria sequester photosynthetic enzymes into microcompartments which facilitate the conversion of carbon dioxide into sugars. Geometric similarities between these structures and self-assembling viral capsids have inspired models that posit microcompartments as stable equilibrium arrangements of the constituent proteins. Here we describe a different mechanism for microcompartment assembly, one that is fundamentally nonequilibrium and yet highly reliable. This pathway is revealed by simulat ...[more]