P38 Mitogen-activated Protein Kinase and Parkinson's Disease.
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ABSTRACT:
SUBMITTER: He J
PROVIDER: S-EPMC6234472 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Publications
P38 Mitogen-activated Protein Kinase and Parkinson's Disease.
He Jianying J Zhong Wenwen W Zhang Ming M Zhang Rongping R Hu Weiyan W
Translational neuroscience 20181112
Parkinson's disease, the second major neurodegenerative disease, has created a great impact on the elder people. Although the mechanisms underlying Parkinson's disease are not fully understood, considerable evidence suggests that neuro-inflammation, oxidative stress, mitochondrial dysfunction, cell proliferation, differentiation and apoptosis are involved in the disease. p38MAPK, an important member of the mitogen-activated protein family, controls several important functions in the cell, sugges ...[more]
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