Ontology highlight
ABSTRACT:
SUBMITTER: Machado FB
PROVIDER: S-EPMC6268082 | biostudies-other | 2012 Feb
REPOSITORIES: biostudies-other
Machado Fabio Bahls FB Yamamoto Rafael Eidi RE Zanoli Karine K Nocchi Samara Requena SR Novello Cláudio Roberto CR Schuquel Ivânia Teresinha Albrecht IT Sakuragui Cássia Mônica CM Luftmann Heinrich H Ueda-Nakamura Tânia T Nakamura Celso Vataru CV de Mello João Carlos Palazzo JC
Molecules (Basel, Switzerland) 20120214 2
Arctium lappa L. (Asteraceae) is used in folk medicine around the World, and shows several kinds of biological activity, particularly in vitro antitumor activity in different cell lines. This study evaluated the antiproliferative activity of the crude extract, semipurified fractions, and isolated compounds from the leaves of A. lappa, through bioassay-guided testing in Caco-2 cells. The crude extract was obtained with a 50% hydroethanolic extract and then partitioned with hexane, ethyl acetate, ...[more]