Ontology highlight
ABSTRACT:
SUBMITTER: Rouault M
PROVIDER: S-EPMC6336816 | biostudies-other | 2019 Jan
REPOSITORIES: biostudies-other
Rouault Marion M Drugowitsch Jan J Koechlin Etienne E
Nature communications 20190117 1
In uncertain and changing environments, optimal decision-making requires integrating reward expectations with probabilistic beliefs about reward contingencies. Little is known, however, about how the prefrontal cortex (PFC), which subserves decision-making, combines these quantities. Here, using computational modelling and neuroimaging, we show that the ventromedial PFC encodes both reward expectations and proper beliefs about reward contingencies, while the dorsomedial PFC combines these quanti ...[more]