Ontology highlight
ABSTRACT:
SUBMITTER: Beber A
PROVIDER: S-EPMC6345803 | biostudies-other | 2019 Jan
REPOSITORIES: biostudies-other
Nature communications 20190124 1
Septins are cytoskeletal filaments that assemble at the inner face of the plasma membrane. They are localized at constriction sites and impact membrane remodeling. We report in vitro tools to examine how yeast septins behave on curved and deformable membranes. Septins reshape the membranes of Giant Unilamellar Vesicles with the formation of periodic spikes, while flattening smaller vesicles. We show that membrane deformations are associated to preferential arrangement of septin filaments on spec ...[more]