Ontology highlight
ABSTRACT:
SUBMITTER: Giuffrida P
PROVIDER: S-EPMC6356995 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Giuffrida Paolo P Vanoli Alessandro A Arpa Giovanni G Bonometti Arturo A Luinetti Ombretta O Solcia Enrico E Corazza Gino Roberto GR Paulli Marco M Di Sabatino Antonio A
Cancers 20181229 1
Small bowel carcinomas (SBC) are uncommon neoplasms, whose predisposing conditions include hereditary syndromes and immune-mediated intestinal disorders including coeliac disease (CD) and Crohn's disease (CrD). Although both CD-associated SBC (CD-SBC) and CrD-associated SBC (CrD-SBC) arise from an inflammatory background, they differ substantially in tumour cell phenotype, frequency of microsatellite instability and nuclear β-catenin expression, as well as in prognosis. For these patients, high ...[more]