Dataset Information
Intramolecular cascade annulation triggered by rhodium(III)-catalyzed sequential C(sp2)-H activation and C(sp3)-H amination.
Ontology highlight
ABSTRACT:
SUBMITTER: Song L
PROVIDER: S-EPMC6404421 | biostudies-other | 2019
REPOSITORIES: biostudies-other
Publications
Intramolecular cascade annulation triggered by rhodium(III)-catalyzed sequential C(sp<sup>2</sup>)-H activation and C(sp<sup>3</sup>)-H amination.
Beilstein journal of organic chemistry 20190227
A rhodium(III)-catalyzed intramolecular oxidative annulation of <i>O</i>-substituted <i>N</i>-hydroxyacrylamides for the construction of indolizinones via sequential C(sp<sup>2</sup>)-H activation and C(sp<sup>3</sup>)-H amination has been developed. This approach shows excellent functional-group tolerance. The synthesized scaffold forms the core of many natural products with pharmacological relevance. ...[more]