Ontology highlight
ABSTRACT:
SUBMITTER: Huang C
PROVIDER: S-EPMC6680903 | biostudies-other | 2019 Jul
REPOSITORIES: biostudies-other
Molecules (Basel, Switzerland) 20190717 14
The functionalization of VHHs enables their application in almost every aspect of biomedical inquiry. Amino modification remains a common strategy for protein functionalization, though is considered to be inferior to site-specific methods and cause protein property changes. In this paper, four anti-β2M VHHs were selected and modified on the amino group by NHS-Fluo. The impacts of amino modification on these VHHs were drastically different, and among all th examples, the modified NB-1 maintained ...[more]