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The Genome and Transcriptome of Fibrolamellar Hepatocellular Carcinoma

ABSTRACT:

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare liver tumor primarily affecting adolescents and young adults. Little is known of the molecular pathogenesis. To characterize the disease we performed RNA sequencing and whole genome sequencing on FL-HCC tumors and adjacent normal tissue. The results demonstrate few consistent differences on the chromosomal level and many hundreds of alterations in the expression of RNA transcripts.

PROVIDER: phs000709 | dbGaP |

SECONDARY ACCESSION(S): PRJNA236539PRJNA236540

REPOSITORIES: dbGaP

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			Action	DRS
	GapExchange_phs000709.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	Study_Report.phs000709.FibrolamellarHepatocellularCarcinoma.v1.p1.MULTI.pdf	Pdf
	manifest_phs000709.FibrolamellarHepatocellularCarcinoma.v1.p1.c1.DS-CA-IRB-MDS.pdf	Pdf
	datadict_v2.xsl	Other

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