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Systemic Lupus Erythematosus Subtypes in a Multi-Ethnic Cohort

ABSTRACT:

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that affects multiple organ systems and varies in severity across different populations. To examine the clinical heterogeneity of SLE, we sought to identify different lupus subtypes within our multi-ethnic cohort using a clustering approach. Additionally, with genome-wide methylation and genotype data generated for our cohort, we applied integrative methods to investigate genetic and epigenetic risk factors. This integrative and computational approach revealed molecular differences associated with phenotypic clusters.

PROVIDER: phs001850 | dbGaP |

REPOSITORIES: dbGaP

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			Action	DRS
	GapExchange_phs001850.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	Study_Report.phs001850.SubtypeSLE.v1.p1.MULTI.pdf	Pdf
	manifest_phs001850.SubtypeSLE.v1.p1.c2.HMB.pdf	Pdf
	datadict_v2.xsl	Other

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