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A Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer

ABSTRACT: This 2 arm study will assess the efficacy and safety of intermittent oral Xeloda, or iv fluorouracil/leucovorin, in combination with intravenous Eloxatin (oxaliplatin) in patients previously treated for metastatic colorectal cancer. Patients will be randomized to receive either 1)XELOX (Xeloda 1000mg/m2 po bid on days 1-15 + oxaliplatin) in 3 week cycles or 2) FOLFOX-4 (oxaliplatin + leucovorin + 5-FU in 2 week cycles. The anticipated time on study treatment is until disease progression, and the target sample size is 500+ individuals.

DISEASE(S): Colorectal Cancer,Colorectal Neoplasms

PROVIDER: 2009841 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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