Browse
Submit Data
Databases
API
Help

Dataset Information

27 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comparison of Transparent Retractable Extension Device and Narrow Band Imaging on Colorectal Adenoma Detection

ABSTRACT: The investigators previously reported that colonoscopy with a transparent retractable extension (TRE) device improved the adenoma detection rate without affecting intubation and withdrawal times. On the other hand, colonoscopy using narrow band imaging (NBI) is expected to lead to higher rate s of adenoma detection. The investigators compared the effects of TRE device on colorectal adenoma detection with those of NBI.

DISEASE(S): Colorectal Neoplasms,Colorectal Cancer Screening

PROVIDER: 2062003 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection

Project description:Colorectal cancer (CRC) is a leading cause of cancer death and its’ incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to detect pre-malignant lesions. Our aim is to evaluate narrow band imaging (NBI) during colonoscopy and serum miRNAs as novel tools for the early detection of colonic sessile serrated lesions (SSL). The investigators will perform a multicenter-randomized-controlled-trial to study the role of NBI in SSL detection.

| 2223112 | ecrin-mdr-crc

Transcription profiling by array of oral squamous cell cancer (OSCC) surgical margins defined by narrow band imaging.

Project description:The purpose of this study was to provide molecular evidence that surgical margin definition using narrow band imaging (NBI) resulted in more complete OSCC excision that conventional while light (WL) imaging. Samples were taken prospectively from 18 patients undergoing surgical resection for intraoral SCC (excluding lip, pharynx and hypopharynx). Biopsies were taken from the tumour and from 5mm beyond each of the abnormal tissue margins defined by WL and NBI. Transcriptional profiling was performed by microarray.

2018-01-17 | E-MTAB-5933 | biostudies-arrayexpress

MicroRNA profiling by array of oral squamous cell cancer (OSCC) surgical margins defined by narrow band imaging.

2018-02-09 | E-MTAB-6470 | biostudies-arrayexpress

Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection

Project description:This study is designed to evaluate the diagnostic accuracy of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) for detection of residual neoplasia in subjects with piecemeal polypectomy scars.

| 2190366 | ecrin-mdr-crc

Narrow-band UVB phototherapy for psoriasis

Project description:Psoriasis is a common chronic inflammatory and hyperproliferative immune-mediated skin disorder. Narrow-band UVB (NB-UVB) phototherapy is a convenient first-line treatment of psoriasis, though the mechanisms underlying its efficacy have not been completely elucidated. In order to improve our understanding of NB-UVB phototherapy, gene expression profiling was used to characterize gene expression in lesional epidermis from psoriasis patients undergoing NB-UVB phototherapy. Increased expression of melanogenesis pathway genes was observed to be the earliest response. At the end of treatment, genes involved in diverse biological processes were affected, such as pigmentation, cell adhesion, ectodermal development and metabolism. The relationship between gene expression and treatment outcome was further studied using Partial Least Squares Discriminant Analysis (PLS-DA). Gene ontology analysis showed that genes responding to phototherapy and highly correlated to treatment outcome were involved in oxidation reduction, growth and mitochondria organization. In particular SPATA18, a key regulator of mitochondria quality, was found to be significantly downregulated in psoriasis, and its upregulation following phototherapy was required for optimal clinical improvement. Our data suggest that oxidation reduction is a critical event for the resolution of psoriatic plaques.

2013-12-23 | GSE53431 | GEO

Study of Narrow Band Imaging in the Characterization of Serrated Lesions

Project description:This study is designed to evaluate the utility of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) in subjects with serrated lesions who do not fulfill the diagnostic criteria of Serrated Polyposis Syndrome (SPS).

| 2187136 | ecrin-mdr-crc

Transcriptomic profiles of advanced colorectal adenomas from 40 Korean patients

Project description:We report the RNA-seq data of 40 advanced colorectal adenoma patients form Dongguk University Ilsan International Hospital. The polyps with a diameter of 1cm or greater were regarded as advenced colorectal adenoma and obtained through colonoscopy. The data consist of 22 tublar adenoma, 6 tublovillous adenoma, 5 sessile serrated adenoma/polyp, 1 traditional serrated adenoma, intramucosal adenocarcinoma, neuroendocrine tumor, hyperplastic polyp, inflammatory polyp, high grade dysplasia, and atypical glands with adjacent hyperplastic mucosa.

2023-08-07 | GSE154548 | GEO

Magnification Narrow Band Imaging Colonoscopy for Hereditary Non-Polyposis Colorectal Cancer Surveillance

Project description:The purpose of this study is to determine whether a new colonoscopic viewing technique called narrow band imaging (NBI)can help doctors detect more patients with at least one pre-cancerous area than conventional colonoscopy using white light alone in patients with genetically inherited high risk for bowel cancer (HNPCC).

| 2028011 | ecrin-mdr-crc

Study on narrow band imaging versus conventional colonoscopy for polyps detection in patients with positive fecal occult blood test undergoing colonoscopy screening

Project description:Background and study aims The detection and removal of adenomatous polyps (small non-cancerous growths that develop in the large bowel) may prevent colorectal cancer and save lives. Colonoscopy is the standard procedure for the detection and removal of polyps. However, colonoscopy still misses between 5% and 24% of polyps, which can result in the development of colorectal cancer. It is also unable to distinguish different types of polyp, leading to the removal of all polyps found, thus increasing the costs and risks. In order to overcome these limitations, there have been many attempts to improve the diagnostic accuracy of colonoscopy. The aim of this study is to find out whether the use of a new endoscopy technology called narrow band imaging (NBI) increases the detection rate of advanced adenomas compared with High Definition White Light colonoscopy (HD-WL). Who can participate? Patients aged 55-64 undergoing colonoscopy What does the study involve? Participants are randomly allocated to undergo colonoscopy with either HD-WL or NBI. The colonoscope is inserted into the rectum and advanced to the cecum (the beginning of the large intestine). The endoscopist carefully explores the whole colon, and the procedure is timed by the endoscopist using a stopwatch. Polyps detected are documented for their size, location and shape, and removed and sent in separate jars for diagnosis by a histopathologist. The number of adenomas and advanced adenomas are counted in both groups.

| 2421677 | ecrin-mdr-crc

Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy

Project description:Narrow band imaging or electronic chromoendoscopy might provide similar adenoma detection capabilities while limiting time spent when compared to conventional chromoendoscopy method.

| 2324220 | ecrin-mdr-crc

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data