Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Simon Fox
PROVIDER: E-MTAB-6470 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Scientific reports 20180116 1
Oral squamous cell carcinoma (OSCC) is a common malignancy for which there is poor prognosis and limited therapeutic options. The objective was to identify mRNA targets of dysregulated miRNAs in OSCC using integrated analysis and understand molecular abnormality in surgical margins. We used biopsies along the spatial axis from normal tissue defined by narrow band imaging (NBI) through conventional white light (WL) margins to tumour from 18 patients undergoing surgical resection for OSCC. Overall ...[more]