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Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab

ABSTRACT: This study is designed to evaluate the mechanism(s) of resistance to the anti-epidermal growth factor receptor (EGFR) antibody panitumumab given in combination with irinotecan in metastatic colorectal carcinoma (mCRC) patients with wild-type Kirsten rat sarcoma-2 virus oncogene (KRAS) tumor status at the time of initial diagnosis.

DISEASE(S): Metastatic Colorectal Cancer,Colorectal Neoplasms

PROVIDER: 2071598 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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