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Treated Blood Cells, Cyclophosphamide, Fludarabine Phosphate, and Aldesleukin in Treating Patients With Cancer

ABSTRACT: RATIONALE: Placing a gene into T cells may improve the body’s ability to recognize cancer cells and build an immune response to fight cancer. Drugs used in chemotherapy, such as cyclophosphamide and fludarabine phosphate, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Biological therapies, such as aldesleukin, may stimulate the immune system in different ways and stop cancer cells from growing. Giving specially treated T cells together with cyclophosphamide, fludarabine phosphate, and aldesleukin may kill more tumor cells. PURPOSE: This phase I clinical trial is studying the side effects and best dose of treated T cells when given together with cyclophosphamide, fludarabine phosphate, and aldesleukin in treating patients with cancer.

DISEASE(S): All,Lung Cancer,Colorectal Cancer,Pancreatic Cancer,Breast Neoplasms,Breast Cancer,Lung Neoplasms,Unspecified Adult Solid Tumor, Protocol Specific,Ovarian Cancer,Gastric Cancer,All Cancers/misc Sites,Stomach Neoplasms,Pancreatic Neoplasms

PROVIDER: 2095938 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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