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Psychological Predictors in Colorectal Cancer Surgery Recovery

ABSTRACT: This is an observation pilot trial aimed to study to the association between mindfulness and other psychological factors, including both protective and risk factors, with recovery of functional ability following colorectal cancer surgery.

DISEASE(S): Colorectal Cancer,Colorectal Neoplasms

PROVIDER: 2292595 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Molecular mechanisms of cannabinoid type II receptor agonists in a mouse model of psychological stress-induced cardiac injury revealed by whole transcriptomic analysis

Project description:To investigate the mechanisms of chronic psychological stress-induced cardiac injury and the protective mechanisms of cannabinoid type II agonists in a model of psychological stress-induced cardiac injury We constructed a mouse chronic psychological stress model based on a chronic unpredictable stress pattern. Mice were randomly divided into control, case (psychological stress group), and treatment groups (post-stress with the cannabinoid type II receptor agonist JWH133) to begin a 3-week psychological stress procedure, and cardiac tissue was subsequently removed for whole-transcriptome sequencing

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An empirical study on the influencing factors and intervention strategies of the quality of life of cancer patients and their families based on positive psychological resources

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Bio-psychological factors in inflammatory bowel diseases (LIMBO study)

Project description:Bio-psychological factors in inflammatory bowel diseases (LIMBO study)

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Human psychological stress plasma

Project description:Blood plasma was collected from 9 naval aviation students 24 hours prior to and no more than 20 minutes after Modular Egress Training (psychological stressor).

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Gene expression and response to psychological therapy

Project description:This study represents the first investigation of genome-wide expression profiles with respect to psychological treatment outcome. Participants (n=102) with panic disorder or specific phobia received exposure-based CBT. Treatment outcome was defined as percentage reduction from baseline in clinician-rated severity of their primary anxiety diagnosis at post-treatment and six month follow-up. Gene expression was determined from whole blood samples at 3 time-points using the Illumina HT-12v4 BeadChip microarray. No changes in gene expression were significantly associated with treatment outcomes when correcting for multiple testing (q<0.05), although a small number of genes showed a suggestive association with treatment outcome (q<0.5, n=20). Study reports suggestive evidence for the role of a small number of genes in treatment outcome. Although preliminary, the findings contribute to a growing body of research suggesting that response to psychological therapies may be associated with changes at a biological level.

2017-02-01 | GSE94119 | GEO

Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure

Project description:Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure

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Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure

Project description:Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure

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Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast

Project description:Psychological stress interferes with bone metabolism, in which miRNAs may play an important role. To gain an insight into skeletal alterations under psychological stress, sRNA sequencing(sRNA-seq) was performed.

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Leukocyte gene expression variation as a function of psychological well-being II

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2015-03-28 | E-GEOD-55762 | biostudies-arrayexpress

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