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Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations

ABSTRACT: This phase II trial studies how well pemigatinib works in treating patients with colorectal cancer with mutations (alterations) in a FGFR gene and that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). Pemigatinib may stop the growth of tumor cells by blocking FGFR, which is needed for cell growth.

DISEASE(S): Stage Ivc Colorectal Cancer Ajcc V8,Fgfr2 Gene Amplification,Fgfr1 Gene Amplification,Stage Iva Colorectal Cancer Ajcc V8,Unresectable Colorectal Carcinoma,Stage Iv Colorectal Cancer Ajcc V8,Carcinoma,Metastatic Colorectal Carcinoma,Fgfr1 Gene Mutation,Fgfr3 Gene Translocation,Fgfr3 Gene Amplification,Stage Iiic Colorectal Cancer Ajcc V8,Stage Iiia Colorectal Cancer Ajcc V8,Stage Ivb Colorectal Cancer Ajcc V8,Fgfr2 Gene Translocation,Fgfr1 Gene Translocation,Fgfr2 Gene Mutation,Colorectal Neoplasms,Stage Iii Colorectal Cancer Ajcc V8,Fgfr3 Gene Mutation,Stage Iiib Colorectal Cancer Ajcc V8

PROVIDER: 2316804 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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