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Impact of Non-Anaemic Iron Deficiency Correction on Exercise Capacity and Perioperative Outcomes in Colorectal Cancer Surgery

ABSTRACT: Interventions: Ferric carboxymaltose, 20mg/kg (up to 1000mg) in 500mL 0.9% sodium chloride administered intravenously. A single dose will be administered under direct observation of the study team. Primary outcome(s): Change in V’O2 peak measured by cardiopulmonary exercise testing. The test will be conducted using an electromagnetically braked cycle ergometer with a 20W ramp protocol.[Measured at baseline and three weeks following administration of study drug] Study Design: Purpose: Treatment; Allocation: Randomised controlled trial; Masking: Blinded (masking used);Assignment: Parallel;Type of endpoint: Efficacy

DISEASE(S): Blood-anaemia,Surgery-other Surgery,Perioperative Medicine,Colorectal Cancer,Cancer-bowel-back Passage (rectum) Or Large Bowel (colon),Anaesthesiology-other Anaesthesiology,Iron Deficiency

PROVIDER: 2467831 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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