Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Clinical effectiveness of daikenchuto (TJ-100) on gastrointestinal symptom after colectomy in colorectal cancer patients with abdominal pain and distention due to a bowel movement disorder.

ABSTRACT: Interventions: Oral administration of test drug (daikenchuto) 5.0 g per dose as a general rule (15 g/day, t.i.d., before meals) from patiant consent day to preoperative day and postoperative day 2 to postoperative day 28. Standard of care. Primary outcome(s): 1) Gastrointestinal symptom. (abdominal pain /distention/ the sensation of incomplete bowel evacuation)2) number of postoperative day to comfirm first evacuation, number of postoperative time to comfirm first flatus, number of bowel movements per day. Study Design: Parallel Randomized

DISEASE(S): Colorectal Cancer Patients With Abdominal Pain And Distention Due To A Bowel Movement Disorder

PROVIDER: 2623756 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Single-cell RNAseq Reveals Seven Classes of Visceral Sensory Neuron

Project description:Integration of nutritional, microbial and inflammatory events along the gut-brain axis can alter bowel physiology and organism behaviour. The principal neural unit in the bowel encoding these stimuli is the visceral sensory neuron with endings at the mucosa, intramurally and along mesenteric blood vessels. Sensory neurons activate reflex pathways and give rise to conscious sensation, however, the diversity and division of function within these neurons is poorly understood. The identification of signalling pathways contributing to visceral sensation is constrained by the current paucity of molecular markers. Here we overcome these limitations by comprehensive transcriptomic profiling and unsupervised clustering of single colonic sensory neurons revealing 7 classes characterised from both lumbar splanchnic (LSN) and pelvic nerves (PN). We identify and classify neurons based on novel marker genes, confirm translation of patterning to protein expression and show subtype-selective differential agonist activation, describing sensory diversity encompassing all modalities of colonic neuronal sensitivity.

2018-02-27 | GSE102962 | GEO

Decoding the m6A expression profiling of spinal cord after spared nerve injury at three time points with RIP-Seq

Project description:We performed gene expression profiling analysis using data obtained from RNA-seq and m6A peaks profiling analysis using data obtained from RIP-Seq of spared nerve injury model at 3rd, 7th, 14th postoperative day and sham group. To investigate the differential m6A expression profiling, we established spared nerve injury model at 3rd, 7th, 14th postoperative day and sham group.

2022-05-06 | GSE202166 | GEO

Longitudinal study of the small urinary extracellular vesicle proteome during living donor kidney transplantation

Project description:Urine was obtained from healthy kidney donors, from transplanted kidneys intrasurgery, at postoperative day 1 and at later timepoints. Exosomes were isolated and measured using nLC-MS/MS. For details, see the accompanying manuscript.

2021-08-30 | PXD005219 | Pride

Altered DNA Methylation of MAP3K6 and HPCAL1 as Potential Predictors for Persistent Trophoblastic Disease

Project description:Patients with molar pregnancy are at risk of developing persistent trophoblastic disease (PTD). Previous study indicated that PTD risk was not related to evacuation time of hydatidiform mole (HM), leading to our hypothesis that HM might be pre-programmed before evacuation to determine the PTD risk. Considering the similarity between PTD and tumorigenesis, we investigated the methylation alterations in PTD conceptus using reduced representation bisulfite sequencing (RRBS), in order to identify potential predictors for PTD.

2015-06-01 | GSE65881 | GEO

Acute phase serum proteome in Cardiac Surgery

Project description:This study is an analysis of the Bern perioperative Biobank, a prospective cohort of adults who underwent cardiac surgery with the use of cardiopulmonary bypass at Bern University Hospital between January and December 2019. Blood samples were taken at induction of anaesthesia and on postoperative day one.

2023-11-27 | PXD046496 | Pride

Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)

Project description:Primary hypothesis: Side-to-end anastomosis is non-inferior to colon J pouch for reconstruction after low anterior resection for rectal cancer in fecal incontinence (Wexner score). Research questions: Are there differences between side-to-end anastomosis and colon J pouch in * bowel function (fecal incontinence, frequency of bowel movements, rectal urgency, incomplete evacuation) * quality of life * sexual function * urinary function * postoperative complications * operation time/ institutional costs

| 2080253 | ecrin-mdr-crc

Triticum aestivum

Project description:BSE-Seq of extreme pools of grain number per spike

| PRJNA1058544 | ENA

Project description:BSA QTLseq analysis for grain number per panicle in rice

| PRJNA1094905 | ENA

RAMPAGE from foreskin keratinocyte (ENCSR517CHX)

Project description:RAMPAGE on primary keratinocytes in day 5.0 of differentiation For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2021-11-04 | GSE187544 | GEO

Registry study of electroacupuncture to improve bowel function in LARS patients after low anterior resection for rectal cancer

Project description:Interventions: Electroacupuncture exposure group:NA;None electroacupuncture exposure group:NA Primary outcome(s): Proportion of patients with reduced defecation dysfunction as judged by LARS scale score;Proportion of reductions from baseline in the average number of bowel movements per day Study Design: Cohort study

| 114147 | ecrin-mdr-crc

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data