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Influence of Continuous Press-Needle Acupoint Stimulation on Promoting the Recovery of Intestinal Function after Colorectal Cancer Surgery: A Randomized Controlled Study

ABSTRACT: Interventions: Press-needle Group:Press-needle stimulates acupoints;Pseudo-needle Group:Pseudo-needle stimulates acupoints Primary outcome(s): Time to first passing flatus Study Design: Parallel

DISEASE(S): Colorectal Cancer

PROVIDER: 2681219 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Skeletal muscle after fine needle stimulation

2007-09-01 | GSE8911 | GEO

Transcription profiling of rat skeletal muscle after fine needle stimulation

Project description:Fine needle stimulation also known as acupuncture is a traditional Chinese medical practice which causes relief of pain. We demonstrated that it caused neovascularization and enhanced recovery of blood perfusion in a ischemic portion of skeletal muscle in rats with hindlimb ischemia. Therefore we evaluated the effect of fine needle stimulation on skeletal muscle at gene expression level Experiment Overall Design: With 0.14mm diameter stainless steel needle, a hundred pricks were applied in a 100 square mili-meter region on addductor portion of the left rat hindlimb. Right hindlimb was left intact as control. 24 hrs after fine needle stimulation, skeletal muscle sample was resected from adductor muscle of fine needle stimulated left hindlimb and non-stimulated right hindlimbs, respectively. Then gene expression analysis with microarray was conducted on each skelatal muscle sample.

2008-06-16 | E-GEOD-8911 | biostudies-arrayexpress

Expression data from paired matched breast cancer Fine needle aspiration (FNA) or Core needle biopsies (CBX)

Project description:Paired FNA and CBX specimens were prospectively collected from 37 breast cancers before any systemic therapy during a biomarker discovery study at The University of Texas M. D. Anderson Cancer Center. We identified 293 probe sets overexpressed in core biopsies; these included five highly coexpressed gene clusters (metagenes) corresponding to immune functions and extracellular matrix components. We compared gene expression profiles of pairs of fine-needle (stroma-poor) and core-needle (stroma-rich) biopsies from 37 cancers to identify stroma-associated genes

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Expression data from paired matched breast cancer Fine needle aspiration (FNA) or Core needle biopsies (CBX)

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METSIM Subcutaneous adipose needle biopsy RNA-seq

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METSIM Subcutaneous adipose needle biopsy ATAC-seq

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The effects of timing of fine needle aspiration biopsies on gene expression profiles in breast cancers

Project description:Paired fine needle aspiration biopsies (FNABs) of breast cancers were taken before (PRE) and after (POST) surgeries from 16 patients and compared the cDNA microarray data to determine the genes that were differentially expressed between the FNABs taken at the two time points. The timing of fine needle aspiration biopsies can be a confounding factor in microarray data analyses in breast cancer. FOS-related genes, which have been implicated in early hypoxia as well as the development of breast cancers, were differentially expressed before and after surgery. Therefore, it is important that future studies take timing of tissue acquisition into account. Keywords: Breast cancer, fine needle, biopsy timing, microarray standardization, early hypoxic genes

2008-09-09 | GSE12072 | GEO

Identification of proteins in the Salmonella SPI-1 type III secretion injectisome needle complex

Project description:We determined the cryo-EM structure of the type III secretion injectisome needle complex. We used LC-MS/MS to idensitfy the constituent proteins showing the predominant presence of the major inner- and outer basal body proteins (PrgH+PrgK and InvG respectively), export apparatus protein SpaP and SpaR, and the rod and needle filament proteins PrgJ and PrgI.

2018-10-16 | PXD010239 | Pride

To observe the effect of individualized ventilation combined with auricular acupoint pressing needle on the quality of emergence from anesthesia and postoperative cognitive function of patients undergoing laparoscopic colorectal cancer surgery o

Project description:Interventions: Auricular acupoint pressing needle:Auricular acupoint pressing needle at the end of the operation;Control group:N/A Primary outcome(s): time to spontaneous respiration recovery ;time to extubation ;time to orientation ;RASS;Mini-mental State Examination(MMSE);heart rate (HR);mean arterial pressure (MAP);cerebral oxygen saturation(rSO2);optic nerve sheath diameter(ONSD);internal jugular vein valve function;time to emergence;Montreal Cognitive Assessment Scale (MOCA) Study Design: Parallel

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TRANSCRIPTOMIC ANALYSIS ON ENDOSCOPIC ULTRASOUND FINE NEEDLE ASPIRATION MATERIALS FROM PRIMARY PANCREATIC ADENOCARCINOMA

Project description:The study aimed to compare the molecular profiles of metastatic, locally advanced, and resected primary pancreatic adenocarcinoma at the genomic and transcriptomic levels. DNA and mRNA were extracted from endoscopic ultrasound-guided fine needle aspiration-biopsy material of primary tumors from 397 patients, and they were subsequently analyzed by targeted deep sequencing and RNAseq.

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