Ontology highlight
ABSTRACT:
INSTRUMENT(S): impact II
ORGANISM(S): Salmonella Typhimurium (strain Lt2 / Sgsc1412 / Atcc 700720)
SUBMITTER: Liam Worrall
LAB HEAD: Natalie Strynadka
PROVIDER: PXD010239 | Pride | 2018-10-16
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
analysis.baf | Other | |||
ceba4fee-0a00-4522-95d2-db0cd4dbc59d_1.mcf | Other |
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Hu J J Worrall L J LJ Hong C C Vuckovic M M Atkinson C E CE Caveney N N Yu Z Z Strynadka N C J NCJ
Nature communications 20180921 1
The bacterial type III secretion system, or injectisome, is a syringe shaped nanomachine essential for the virulence of many disease causing Gram-negative bacteria. At the core of the injectisome structure is the needle complex, a continuous channel formed by the highly oligomerized inner and outer membrane hollow rings and a polymerized helical needle filament which spans through and projects into the infected host cell. Here we present the near-atomic resolution structure of a needle complex f ...[more]