The effect of usual versus limited fluid therapy in children undergoing abdominal, chest and genitourinary surgery.

ABSTRACT: Intervention1: Restricted fluid therapy: During intra-operative period, restricted fluid therapy group will receive maintenance and deficit correction as per Holliday-Segar formula and blood loss replacement (3:1 with Ringers lactate and 1:1 with blood according to anaesthesiologists decision). Fluid bolus will be given at 5ml/kg if stroke volume variation (SVV) in electrical cardiometry is more than 15% persistently for more than 5 min. At the end of surgery number of fluid boluses, serum lactate, sodium, potassium, calcium, blood urea and creatinine will be measured. Chest x ray will be taken in immediate post-operative period to look for signs of fluid overload. Assessment for nausea and vomiting will be done, weight will be checked if posssible. On post-operative day 2, blood urea and serum creatinine will be checked. Duration of hospital stay will be noted. Control Intervention1: Standard fluid therapy: During intra-operative period, standard fluid therapy group will receive maintenance and deficit fluid correction as per Holliday-Segar formula, blood loss replacement and 3rd space loss replacement(4-7ml/kg for thoracotomy, 5-10ml/kg for abdominal surgery). Electrical cardiometry will be monitored in this group also. At the end of surgery number of fluid boluses, serum lactate, sodium, potassium, calcium, blood urea and creatinine will be measured. Chest x ray will be taken in immediate post-operative period to look for signs of fluid overload. Assessment for nausea and vomiting will be done, weight will be checked if posssible. On post-operative day 2, blood urea and serum creatinine will be checked. Duration of hospital stay will be noted. Primary outcome(s): 1.Postoperative hypernatremia 2.Rise in serum lactate 3.Rise in blood urea 4.Rise in serum creatinine Timepoint: At the end of surgery

DISEASE(S): Congenital Absence, Atresia And Stenosis Of Large Intestine, Part Unspecified,Congenital Cystic Lung,Congenital Malformation Of Male Genital Organ, Unspecified,Congenital Malformation Of Kidney,unspecified,Congenital Absence, Atresia And Stenosis Of Anus With Fistula,Benign Neoplasm Of Mediastinum,Congenital Absence, Atresia And Stenosis Of Other Parts Of Large Intestine,Atresia Of Esophagus With Tracheo-esophageal Fistula,Benign Neoplasm Of Adrenal Gland,Congenital Hydronephrosis,Biliary Cyst,Congenital Malformation,Benign Neoplasm Of Colon, Unspecified,Congenital Malformation Of Digestive System, Unspecified,Congenital Malformation Of Esophagus, Unspecified,Congenital Fistula Of Rectum And Anus,Atresia Of Bile Ducts,Congenital Cyst Of Mediastinum,Congenital Hiatus Hernia,Benign Neoplasm Of Other Specifiedintrathoracic Organs,Celiac Disease,Choledochal Cyst,Congenital Malformation Of Intestine, Unspecified

PROVIDER: 28494 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR