Project description:The French Institute for Public Health Surveillance monitors health events of potential international importance occurring worldwide to provide timely warning to French health authorities. We reviewed the nature and place of occurrence of the last 200 events. From an individual country's perspective, the need for multiple sources is emphasized.
Project description:Background The goal of this research project was to identify and suggest means of filling the gaps/needs in Canadian research activity and public policy action on the income and health relationship. Methods The research consisted of an environmental scan and analysis of 321 empirical research pieces from Canada (n=241), the United Kingdom (n=40) and Finland (n=40) followed by a systematic gaps/needs analysis of these studies by members of three advisory committees, consisting of researchers and policy advocates. These data were complemented by key informant interviews with researchers from Canada, the UK and Finland. The gaps/needs were then reviewed and assigned priority rankings by members of the three advisory committees. Findings Numerous gaps/needs in Canadian research on income and health were apparent. They fell into five main areas: (a) training and capacity building in addressing income as a health determinant; (b) developing adequate data and measures; (c) researching specific substantive health issues; (d) researching specific public policy areas; and (e) developing an understanding of the pathways and mechanisms mediating the income and health relationship. Members of the advisory committees achieved a high level of agreement concerning these gaps/needs and means of reducing them. Conclusions The Canadian Institutes of Health Research (CIHR) and the Institute of Population Health should target specific research initiatives to help fill the identified gaps in knowledge. They should also work together with public policy institutes to synthesize findings concerning income, its distribution, and health, and help distribute these findings to the public in general and policy-makers in particular. Electronic Supplementary Material Supplementary material is available for this article at 10.1007/BF03405393 and is accessible for authorized users.
Project description:Background A review of infectious disease research activity and capacity was performed in British Columbia and linked to a process for identifying needs, gaps and opportunities from a public health perspective. Methods The study was organized in three phases: an environmental scan to describe current research activity in BC; a consultation to identify needs, gaps and opportunities with those conducting research (key informants) and the end users of research results (stakeholders); and a prioritization of the research needs emerging from the consultation. Results Analysis and synthesis of the consultation data resulted in the identification of nine research themes, which were prioritized in the following order: efficacy and cost-benefit, disease patterns, emerging infectious disease, immunology and vaccines, disease-specific research, health promotion and communications, safe food and water, knowledge translation research and genomics. Six capacity-building themes were also identified: attraction and retention, education and training, collaboration and networks, funding, dissemination of findings, and public health input, surveillance, informatics and databases. Interpretation The findings were helpful in developing a multi-disciplinary, multi-level infectious disease research agenda linking researchers in universities, hospitals and public health institutions with practitioners and policy-makers in British Columbia’s public health system. The approach is both feasible and important to undertake at the national level. Electronic Supplementary Material Supplementary material is available for this article at 10.1007/BF03405394 and is accessible for authorized users.
Project description:BackgroundFew studies have explored the potential for family dynamics to hinder or promote help-seeking and disclosure behaviours among adolescents who self-harm or experience suicidality. We sought to examine whether family dynamics may influence self-harm-related disclosure to parents or other family members and online help-seeking.MethodsWe identified youths, 14-17 years, in the 2014 Ontario Child Health Study (OCHS) who self-reported past-year suicidal ideation (with or without a suicide plan or past suicide attempt[s]) and/or non-suicidal self-harm. The OCHS is a provincially representative, cross-sectional survey. The person most knowledgeable about the adolescent, usually the mother, reported family dynamics: family dysfunction and positive and negative parenting practices. We used logistic regression to generate adjusted odds ratios.ResultsA total of 359 adolescents positively endorsed past-year suicidal ideation and/or non-suicidal self-harm. Disclosure and help-seeking were common (≥67.3% and ≥25.6%, respectively). Adolescents experiencing suicidal ideation and greater family dysfunction were more likely to share their suicidal thoughts with non-family compared to not telling anyone (OR = 1.09, 95% CI: 1.01 to 1.18) and were less likely to tell their parents or other family members about their suicidal thoughts when compared to non-family such as teachers, partners, or friends (OR = 0.82, 95% CI: 0.71 to 0.94). Positive parenting was not associated with any form of disclosure or online help-seeking for non-suicidal self-harm or suicidal ideation. As adolescent exposure to negative parenting increased, so did the likelihood that they would seek help online for their suicidal thoughts (OR = 1.22, 95% CI: 1.08 to 1.37). Sensitivity analyses replicated or were very similar to findings from the main models.ConclusionWe found that negative family dynamics were related to reduced sharing of suicidal thoughts with parents or other family members and greater online help-seeking. Our findings suggest that the importance of negative family dynamics to disclosure and support-seeking for adolescent suicidality may be under-recognized.
Project description:Monkeypox virus: Genome sequencing by Pathogen Genomic Lab, Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo
Project description:We wish to respond to the commentary of de la Iglesia et al. [1]. Studies comparing sleep in different communities have different goals. One frequent goal has been to determine how sleep is affected by manipulating specific 'modern' conditions. Many studies have investigated the effect of artificial light and electronic entertainment. Such studies have clearly shown that light, particularly blue light, delays sleep onset [2]. Studying the effect of artificial light on sleep was not a goal of our study.
Project description:Background: Spinal fusion for scoliosis generates moderate to severe pain intensity. There are currently no instruments available to measure adolescents' satisfaction regarding post-spinal fusion pain management. Aims: To develop and validate a scale on satisfaction of adolescents regarding pain management following spinal fusion for scoliosis. Methods: A methodological design was used to develop and validate the French-Canadian scale "Satisfaction des Adolescents de la gestion de la Douleur postopératoire - Scoliose idiopathique (SAD-S)". A modified Delphi method, with seven healthcare professionals and 10 adolescents, was used to establish content validity of the SAD-S. A pre-test of the scale was conducted with 10 adolescents post-spinal fusion. The final version of the scale was validated through a pilot study with 98 adolescents following their surgery. Results: The SAD-S scale includes a total of 13 items. Principal component analysis yielded a two-factor structure (2 subscales): 1) Pain management education and 2) Education regarding medication. These two factors explained 47,8% of the total variance for satisfaction. A Cronbach's alpha of 0,84 was obtained for internal consistency. Conclusion: Validation of the SAD-S scale showed that it has good psychometric properties with this population. Further validation is required with a larger sample to pursue its validation.
Project description:Primary objectives: Analyser le profil de la réponse inflammatoire cutanée des patients traités par anti-EGFR et de rechercher le lien avec la réponse radiologique
Primary endpoints: Le critère de jugement principal est la variation du taux des différents marqueurs inflammatoires cutanés présents au niveau des biopsies cutanées pré et post-thérapeutiques en fonction de la réponse radiologique.