Genomics

Dataset Information

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PCGP MEL WXS - samples


ABSTRACT: DATA FILES FOR PCGP SJMEL WXS

PROVIDER: EGAD00001001246 | EGA |

REPOSITORIES: EGA

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Publications


Despite remarkable advances in the genomic characterization of adult melanoma, the molecular pathogenesis of pediatric melanoma remains largely unknown. We analyzed 15 conventional melanomas (CMs), 3 melanomas arising in congenital nevi (CNMs), and 5 spitzoid melanomas (SMs), using various platforms, including whole genome or exome sequencing, the molecular inversion probe assay, and/or targeted sequencing. CMs demonstrated a high burden of somatic single-nucleotide variations (SNVs), with each  ...[more]

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