Dataset Information
PCGP MEL RNASEQ - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001001247 | EGA |
REPOSITORIES: EGA
Publications
The genomic landscape of childhood and adolescent melanoma.
The Journal of investigative dermatology 20140930 3
Despite remarkable advances in the genomic characterization of adult melanoma, the molecular pathogenesis of pediatric melanoma remains largely unknown. We analyzed 15 conventional melanomas (CMs), 3 melanomas arising in congenital nevi (CNMs), and 5 spitzoid melanomas (SMs), using various platforms, including whole genome or exome sequencing, the molecular inversion probe assay, and/or targeted sequencing. CMs demonstrated a high burden of somatic single-nucleotide variations (SNVs), with each ...[more]