Genomics

Dataset Information

0

DNA_Methylation_450K


ABSTRACT: BLUEPRINT DNA methylation profiles of monocytes, neutrophils and T cells from healthy donors

PROVIDER: EGAD00010000850 | EGA |

REPOSITORIES: EGA

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Publications


<h4>Background</h4>A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability.<h4>Results</h4>We apply a novel analytical approach to measure and compare transcriptional and epigenetic variability genome-wide across CD14<sup>+</sup>CD16<sup>-</sup> monocytes, CD66b<sup>+</sup>CD16<sup>+</sup> neutrophils, and CD4<sup>+</sup>CD45RA<sup>+</sup> naïve T cells from the same 125  ...[more]

Publication: 1/2

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