Other

Dataset Information

1K

King's College London


ABSTRACT: Organisation EGAO00000000106

PROVIDER: EGAO00000000106 | EGA |

REPOSITORIES: EGA

altmetric image

Publications


Germ-line genetic control of gene expression occurs via expression quantitative trait loci (eQTLs). We present a large, exon-specific eQTL data set covering ten human brain regions. We found that cis-eQTL signals (within 1 Mb of their target gene) were numerous, and many acted heterogeneously among regions and exons. Co-regulation analysis of shared eQTL signals produced well-defined modules of region-specific co-regulated genes, in contrast to standard coexpression analysis of the same samples.  ...[more]

Similar Datasets

| EGAO00000000724 | EGA
| EGAO00000000053 | EGA
| EGAO00000000373 | EGA
| EGAO00000000110 | EGA
| EGAO00000000613 | EGA
| EGAO00000000420 | EGA
| S-EPMC8366163 | biostudies-literature
| S-EPMC3094330 | biostudies-literature
| S-EPMC3912700 | biostudies-literature
| EGAO00000000887 | EGA