Dataset Information
WTCCC case-control study for Coronary Artery Disease - Combined Controls
Ontology highlight
ABSTRACT:
PROVIDER: EGAS00000000004 | EGA |
REPOSITORIES: EGA
Publications
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Nature 20070601 7145
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix GeneChip 500K Mapping Array Set) undertaken in the British population, which has examined approximately 2,000 individuals for each of 7 major diseases and a shared set of approximately 3,000 controls. Case-control comparisons identified 24 independent association signals at P < 5 ...[more]