Transcriptomics

Dataset Information

0

A compendium of antibiotic-induced transcription profiles reveals broad regulation of P. multocida virulence genes


ABSTRACT: Treatment of bacteria with antibiotics at or close to the inhibitory concentration leads to specific transcriptional responses often affecting target genes and targets pathways. A dataset of transcriptional profiles (compendium) induced by antibiotics with known mode-of-action (MoA) can be used to gain information on the putative MoA of novel substances with unknown MoAs. We used a Pasteurella multocida microarray to generate a compendium of transcriptional profiles and to obtain information on the putative MoA of a novel antibiotic compound. We also show a strong impact of the bacteriostatic antibiotics on P. multocida virulence gene transcription. Keywords: antibiotica treatment, time course

ORGANISM(S): Pasteurella multocida Pasteurella multocida subsp. multocida str. Pm70

PROVIDER: GSE10051 | GEO | 2008/06/01

SECONDARY ACCESSION(S): PRJNA108625

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2008-06-01 | E-GEOD-10051 | biostudies-arrayexpress
2016-03-02 | E-GEOD-77721 | biostudies-arrayexpress
2016-03-02 | GSE77721 | GEO
2016-03-14 | PXD003586 | Pride
2009-09-01 | E-GEOD-12779 | biostudies-arrayexpress
2020-07-23 | PXD016074 | Pride
2020-07-23 | PXD016001 | Pride
| PRJNA525062 | ENA
2022-03-02 | GSE196834 | GEO
2022-03-14 | GSE198087 | GEO