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ICG-001 activates a series of ER stress response genes in monocyte derived macrophages (MDMs)

ABSTRACT: By screening a target-focused Wnt-sgnaling small compound library we identified the Wnt-modulator ICG-001 as inihibitory for activating the mitochondrial fission protein Drp1. To explore how ICG-001 might act we undertook gene expression profiling in iCG-001 treated primary macrophages.

ORGANISM(S): Homo sapiens

PROVIDER: GSE102117 | GEO | 2018/01/12

SECONDARY ACCESSION(S): PRJNA396732

REPOSITORIES: GEO

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