Genomics

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RNAseq and ChIPseq on Mouse Embryonic Stem Cells and Sorted Mesendoderm Progenitor Cells [ChIP-seq]


ABSTRACT: We mapped the enhancer and long non-coding transcriptional landscape during mesendoderm specification. Mesendodermal progenitors were sorted from differentiating ESCs according to Eomes expression. Enhancer usage was coordinated with mesendoderm-specific expression of key lineage-determining transcription factors. We demonstrated that many of these enhancers are associated with the expression of lncRNAs.

ORGANISM(S): Mus musculus

PROVIDER: GSE103262 | GEO | 2017/10/10

SECONDARY ACCESSION(S): PRJNA401912

REPOSITORIES: GEO

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