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LncRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

ABSTRACT: The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant mRNA and lncRNA expressions may be involved in the pathogenesis and development of endometriosis. This study therefore aims to survey key TFs, genes and lncRNAs and further understand the mechanism of endometriosis. Paired expression profiling of mRNA and lncRNA in ectopic endometria compared with eutopic endometria were determined by high-throughput sequencing techniques in eight patients with ovarian endometriosis. Our study presents a unique insight into the regulatory network of this enigmatic disorder and possibly provides clues regarding replacement therapy of endometriosis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE105764 | GEO | 2018/02/14

REPOSITORIES: GEO

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