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Xrn1 activates transcription, translation and decay of mRNAs encoding membrane proteins

ABSTRACT: To study the role of the exonuclease Xrn1 in translational control, we performed ribosome profiling and RNA-seq in Xrn1-depleted cells. By using an auxin-inducible degron, we were able to study immediate effects of Xrn1 depletion in translational control. Therefore, we could overcome experimental limitations associated to stable deletion mutants.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE109734 | GEO | 2019/02/08

REPOSITORIES: GEO

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