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Resident macrophage enhances an autoimmune lesion in Sjögren's syndrome

ABSTRACT: Macrophages are critical regulators of immune responses, and link innate immunity to acquired immunity. The precise mechanism of the pathogenesis of autoimmune diseases through tissue-resident macrophage is unclear. The role of the tissue-resident macrophages in the onset or development of autoimmunity was investigated using a murine model for Sjögren’s syndrome.

ORGANISM(S): Mus musculus

PROVIDER: GSE110816 | GEO | 2018/02/21

REPOSITORIES: GEO

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